noun, plural e·pis·ta·ses [ih-pis-tuh-seez] /ɪˈpɪs təˌsiz/.

  1. Genetics. a form of interaction between nonallelic genes in which one combination of such genes has a dominant effect over other combinations.
  2. Medicine/Medical.
    1. the stoppage of a secretion or discharge.
    2. a scum that forms on a urine specimen upon standing.


  1. obsolete scum on the surface of a liquid, esp on an old specimen of urine
  2. med the arrest or checking of a bodily discharge, esp bleeding
  3. Also called: hypostasis genetics the suppression by a gene of the effect of another gene that is not its allele

medical Latin, from Greek epistasis “a stopping, stoppage,” from epi “upon” (see epi-) + stasis “a stopping or standing” (see stasis).

n. pl. e•pis•ta•ses (-sēz′)

  1. A film that forms over the surface of a urine specimen.
  2. An interaction between nonallelic genes, especially an interaction in which one gene suppresses the expression of another.
  3. The suppression of a bodily discharge or secretion.

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