- Middle West.
- Also Mid·west·ern. Middle Western.
- the N central part of the US; the region consisting of the states from Ohio westwards that border on the Great Lakes, often extended to include the upper Mississippi and Missouri valleys
n.1926, in U.S. geographical sense, from earlier Midwestern (1889) in reference to a group of states originally listed as W.Virginia, Kentucky, Tennessee, Missouri, Kansas, and Arkansas; now generally meaning states somewhat further northwest. Related: Midwesterner.