verb (used with object), ox·y·gen·at·ed, ox·y·gen·at·ing.
- to treat, combine, or enrich with oxygen: to oxygenate the blood.
- an apparatus that oxygenates the blood, esp while a patient is undergoing an operation
- to enrich or be enriched with oxygento oxygenate blood
- To treat, combine, or infuse with oxygen.
- To combine or mix with oxygen, as in a physical, chemical, or biological system. Blood is oxygenated in the lungs.