- having or showing no regard; heedless; unmindful (often followed by of).
- without concern as to advice, warning, hardship, etc.; anyway: I must make the decision regardless.
- regardless of, in spite of; without regard for: They’ll do it regardless of the cost.
- (usually foll by of) taking no regard or heed; heedless
- in spite of everything; disregarding drawbacksto carry on regardless