1. a reply; answer.
  2. a reply to an answer.
  3. Law. the reply of the plaintiff or complainant to the defendant’s plea or answer.
  4. reverberation; echo.
  5. a copy.
  6. the act or process of replicating, especially for experimental purposes.
  7. Genetics. the process by which double-stranded DNA makes copies of itself, each strand, as it separates, synthesizing a complementary strand.


  1. a reply or response
  2. law (formerly) the plaintiff’s reply to a defendant’s answer or plea
  3. biology the production of exact copies of complex molecules, such as DNA molecules, that occurs during growth of living organisms
  4. repetition of a procedure, such as a scientific experiment, in order to reduce errors
  5. a less common word for replica

late 14c., “action of folding back,” also “legal reply (third step in the pleadings in a common-law action), rejoinder,” from Anglo-French replicacioun, Old French replicacion “reply, answer,” from Latin replicationem (nominative replicatio) “a reply, repetition, a folding back,” from past participle stem of replicare “to repeat, reply,” literally “to fold back” (see reply (v.)). Meaning “a copy, reproduction” first recorded 1690s. Sense in genetics is from 1948.


  1. The act or process of duplicating or reproducing something.
  2. Autoreproduction.

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